Saturday, December 31, 2011

Best broadband suburbs in South Africa

Rudolph Muller

Rudolph Muller is the editor at MyBroadband and covers telecoms and broadband news. Rudolph comes from an academic background, but left the University of...

Latest Net Index statistics reveal which suburbs in South Africa enjoys the highest average broadband speeds

Ookla?s Net Index shows that Parow is the suburb with the highest average broadband speed in South Africa, followed by Witbank and Sandton.

Ookla?s Net Index uses data from the web based speed test service Speedtest.net. The service ranks consumer download speeds around the globe using results from the past 30 days where the average distance between the client and the test server is less than 300 miles (482.8km).

Results for South African download speeds were obtained by analyzing data from 280,820 Speedtest.net tests which were performed between 13 November 2011 and 12 December 2011. City (suburb) rankings require at least 1,000 unique IP addresses for a given city.

  1. Parow 9.37 Mbps
  2. Witbank 5.02 Mbps
  3. Sandton 3.92 Mbps
  4. Pretoria 3.91 Mbps
  5. Midrand 3.86 Mbps
  6. Bellville 3.68 Mbps
  7. Randburg 3.62 Mbps
  8. Johannesburg 3.49 Mbps
  9. Cape Town 3.43 Mbps
  10. Rustenburg 3.29 Mbps

It should however be noted that the average speeds are calculated using all Speedtest.net results which may include speed tests from core networks and other non-commercial broadband links.

The high average speed in Parow of 9.37Mbps, for example, may well be a result of a high number of tests from high speed connections other than commercial broadband services.

Best broadband suburbs in South Africa

Best broadband suburbs in South Africa

Tags: broadband, Headline, ookla, speedtest.net

Source: http://mybroadband.co.za/news/broadband/39879-best-broadband-suburbs-in-south-africa-2.html

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Cyclone Thane kills at least 33 in southeast India (Reuters)

CHENNAI, Dec 31 (AlertNet) ? At least 33 people died when Cyclone Thane hit coastal southern India near the former French colony of Pondicherry, officials said Saturday, causing thousands to evacuate and damaging roads, buildings and power lines.

Thane hit Tamil Nadu state Friday with winds of up to 135 kmph (83 mph) and tidal surges of up to 1.5 meters (5 feet). About 6,000 coastal villagers were forced to seek safety in relief shelters, the state's Chief Minister J Jayalalitha said.

"Most of the deaths in the district were because of house collapses and electrocution," said V. Amuthavalli, an official in Cuddalore district, the worst-hit area.

At least seven people died in Pondicherry, popular with Indian and foreign tourists for its beaches and gardens, a town official said. A French foreign ministry spokesman said a French citizen was among those killed.

"France would like to express its profound solidarity with the authorities and people of India in the wake of cyclone Thane," the spokesman said.

Also, the foreign ministry website has advised French people planning to travel to the area for the New Year to delay their plans for a few days.

Trees were uprooted and roads damaged along a 40 km (25 mile) stretch of coast that includes the township of Auroville, known for its avant-garde architecture and yoga community.

The storm quickly lost strength over land and Saturday morning India's weather office said it was now a depression that would bring some heavy rain across the south.

India's cyclone season generally lasts from April to December with severe storms often causing dozens of deaths, evacuations of tens of thousands of people from low-lying villages and widespread crop and property damage.

In 1999, a "super-cyclone" battered the coast of the eastern state of Orissa for 30 hours with wind speeds reaching 300 kph (186 mph). It killed 10,000 people.

(Writing by Frank Jack Daniel with additional reporting by Vicky Buffery in Paris; Editing by Ed Lane)

(AlertNet is a global humanitarian news service run by Thomson Reuters Foundation. Visit www.trust.org/alertnet)

Source: http://us.rd.yahoo.com/dailynews/rss/asia/*http%3A//news.yahoo.com/s/nm/20111231/wl_nm/us_india_cyclone_thane

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Crutchfield Heights Baptist Church

Submitted by tcarpenter on December 30, 2011 - 12:19pm

Address:?

600 S Dewey Ave

Sherman

TX

75090

Phone:?

(903) 892-9700

Source: http://www.heralddemocrat.com/content/crutchfield-heights-baptist-church.html

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Friday, December 30, 2011

Newsweek: "There is no logical reason why a minnow-size [debt crisis in Greece] should have ballooned into an existential threat" http://t.co/MPPBwAgz

Twitter / Newsweek: "There is no logical reaso ... Loader "There is no logical reason why a minnow-size [debt crisis in Greece] should have ballooned into an existential threat"

Source: http://twitter.com/Newsweek/statuses/152162667732279296

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Video: Injured model spent Christmas with family

Lauren Scruggs' family says she's making remarkable progress in her recovery since accidentally walking into an airplane's spinning propeller. NBC's Amy Robach reports.

Related Links:

TODAY.com home page

Source: http://video.today.msnbc.msn.com/today/45803640/

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US teen, 2 others found dead in western Mexico (AP)

MORELIA, Mexico ? Mexican prosecutors say teeth and clothing remnants were used to identify a suburban Chicago teenager whose charred remains were found on Christmas Eve in western Mexico.

The bodies of 18-year-old Alexis Marron of Rolling Meadows and two Mexican friends were found in a burned-out car in rural Michoacan, a western state plagued by violence linked to drug trafficking.

Prosecutors' documents obtained Wednesday by The Associated Press quote an uncle saying Marron was on his way to see a girlfriend, apparently without telling some of his relatives.

Marron was a U.S. citizen and high school student. His family was from Michoacan.

Friends in suburban Chicago have been holding vigils and setting up memorial Facebook pages.

Source: http://us.rd.yahoo.com/dailynews/rss/mexico/*http%3A//news.yahoo.com/s/ap/20111228/ap_on_re_la_am_ca/lt_mexico_us_teen_killed

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Thursday, December 29, 2011

Patriots, 49ers lead Pro Bowl rosters (AP)

NEW YORK ? The usual names ? Tom Brady, Ray Lewis, Troy Polamalu, Tony Gonzalez ? are headed for Hawaii, barring a trip to the Super Bowl.

Joining them at the Pro Bowl will be the not quite so familiar, from Rob Gronkowski to Jimmy Graham, from Marshal Yanda to Earl Thomas.

The thrill is equal, whether it's eight-time invitee Ed Reed or his Baltimore Ravens teammate, newcomer Yanda.

"I am ecstatic, that is really the only thing I can say," said Yanda, a backup at guard to New England's Logan Mankins and Brian Water. "This is such a great honor, something that I never really expected. When I made it to the NFL, I was so happy to be on a team and playing in the league, and now, to be a part of a Pro Bowl team is something very special."

Or as old hand safety Reed put it Tuesday, "It is definitely an honor and blessing. To come back after an injury last year and to be voted by my peers and fans is special."

There are seven Ravens on the AFC squad, equaling the number of Green Bay Packers for the NFC. But they didn't lead their conferences in voting by players, coaches and fans.

Brady is one of eight Patriots and Patrick Willis one of eight 49ers to make the Jan. 29 game.

"It's awesome," said 49ers punter Andy Lee, one of four Bay Area kickers to make it. "I think everybody is deserving. I think some guys are deserving who aren't going. Hopefully we won't be there, hopefully we'll be in the Super Bowl."

Players who make the Super Bowl will be replaced on the Pro Bowl rosters.

Still, it's a sunny, balmy consolation prize to journey to Honolulu.

"It's a nice honor," Texans running back Arian Foster said. "People that love watching the game, people that love playing it and also coaches that have been around it for 20-some-odd years ... it's the highest compliment you can get in this league is when you're voted in by people who know the game. It's just fun."

Brady is one of seven starters from New England (12-3). The others are receiver Wes Welker, tight end Gronkowski, defensive tackle Vince Wilfork, defensive end Andre Carter, Waters and Logan Mankins. Special-teamer Matthew Slater is the other New England representative.

Linebacker Willis, defensive end Justin Smith, cornerback Carlos Rogers and tackle Joe Staley will start for the NFC from the 49ers (12-3), who had only Smith and Willis make the Pro Bowl last year.

Green Bay's Rodgers is the starting NFC quarterback, backed by record-setting Drew Brees of New Orleans (12-3).

"It does have special significance, because when I was voted in in 2009, I was the third guy and I was very thankful to be voted in, and got the opportunity to start because of some injuries and guys not going," Rodgers said. "It's great to be voted in as a starter, that means a lot to me and it's a special honor."

Four of the NFL's biggest headline makers this season did not get voted in by players, coaches and fans: Lions defensive tackle Ndamukong Suh, Steelers linebacker James Harrison, Panthers rookie quarterback Cam Newton, and Denver quarterback Tim Tebow.

Suh might have lost support after drawing a two-game suspension for stomping an opponent, and Harrison's one-game suspension for his helmet-to-helmet hit on Browns quarterback Colt McCoy might have reduced his support.

Fifteen first-time Pro Bowl selections made the NFC squad, including Rogers, Staley and safety Dashon Goldson of the 49ers. Thirteen AFC players were first-time selections, including Gronkowski, Carter and Slater of New England. Carter is on injured reserve (left quadriceps) and won't play.

"If you look around the NFC, you see a ton of amazing and talented players at tight end," said the Saints' Graham, the starter at the position and a first-time Pro Bowl player. "And to be thought of in that company by my peers, the head coaches and the fans who follow the NFL is something I take seriously."

Fourteen teams from each conference were represented, with St. Louis (2-13) and Washington (5-10) drawing blanks in the NFC, Buffalo (6-9) and Tennessee (8-7) shut out in the AFC.

Pittsburgh (11-4), New Orleans and Chicago (7-8) each had five representatives.

Three rookies were chosen: Denver linebacker Von Miller, Cincinnati receiver A.J. Green, and Arizona cornerback Patrick Peterson, selected as a kick return specialist. He has tied an NFL record with four punt runbacks for TDs this season.

"As I've said before, A.J. is the best first-round draft pick that I've ever been around," Bengals coach Marvin Lewis said. "He has shown the other players in this league, and the fans, that he deserved this honor. I have not seen a receiver better than he is at getting to the ball."

NFC special-teamers included two 49ers: Lee and record-setting kicker David Akers; Peterson; and Corey Graham of Chicago.

For the AFC, the Raiders' Sebastian Janikowski is the kicker, Shane Lechler the punter. The kick return specialist is Pittsburgh WR Antonio Brown, and the special-teams player is Slater.

NFC starters will be Rodgers, Eagles running back LeSean McCoy, Packers fullback John Kuhn, Graham, Panthers center Ryan Kalil, Saints guards Jahri Evans and Carl Nicks, Eagles tackle Jason Peters and Staley, Cardinals wide receiver Larry Fitzgerald and Lions wide receiver Calvin Johnson on offense.

"I think it's the fact that I'm versatile at fullback," Kuhn said when asked why he was selected. "I can play the traditional fullback role and lead block, and the coaches also entrust the ball-carrying opportunities that I have. I think the combination of the two of those really gets my name out there."

On defense, it will be Vikings end Jared Allen and Eagles end Jason Babin, Cowboys tackle Jay Ratliff and Smith, Packers outside linebacker Clay Matthews and Cowboys outside linebacker DeMarcus Ware, inside linebacker Willis, Packers cornerback Charles Woodson and Rogers, Seahawks safety Earl Thomas and Cardinals safety Adrian Wilson.

AFC starters will be Brady, Ravens running back Ray Rice and fullback Vonta Leach, Gronkowski, Steelers center Maurkice Pouncey, Mankins and Waters at guard, Browns tackles Joe Thomas and Dolphins tackle Jake Long, Welker and Steelers wide receiver Mike Wallace.

On defense, it will be Broncos end Elvis Dumervil replacing Carter, Colts end Dwight Freeney, Wilfork and Ravens tackle Haloti Ngata, Miller and Ravens outside linebacker Terrell Suggs, Lewis, Jets cornerback Darrelle Revis and Broncos cornerback Champ Bailey, Steelers safety Troy Polamalu and Reed.

"What makes it special to me now is I'm in my 13th year, and you don't see guys going to the Pro Bowl this late in their career," Bailey said. "For me to be able to do it, it feels good, and it feels like I've got a lot more left. It feels good that I'm still playing at a high level."

Source: http://us.rd.yahoo.com/dailynews/rss/sports/*http%3A//news.yahoo.com/s/ap/20111228/ap_on_sp_fo_ne/fbn_pro_bowl

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Japan Average Gasoline Price Posts First Fall in Three Weeks

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Home / All, Mkt News / Japan Average Gasoline Price Posts First Fall in Three Weeks

TOKYO (MNI) ? The average price of regular gasoline in Japan this
week stood at Y143.4 ($1.84) per liter, or $6.99 per gallon, down from
Y143.6 the previous week, and marking the first fall in three weeks,
data released by the Oil Information Center showed on Wednesday.

The average price of high-octane gasoline stood at Y154.2 per
liter, down from Y154.4 last week. It hit a record high of Y196.0 on
Aug. 4, 2008.

The average price of diesel fuel was at Y124.3 per liter this week,
down from Y124.4 the previous week. That compares with the record high
of Y167.4 recorded on Aug. 4, 2008.

The average over-the-counter price of kerosene for heating stood at
Y1,604 per 18 liters this week, down from Y1,605 in the last week. It
posted a record high of Y2,378 on Aug. 11, 2008.

The average home-delivery kerosene price this week was at Y1,727
per 18 liters this week, unchanged from the last week. It hit a record
high of Y2,484 on Aug. 11, 2008.

tokyo@marketnews.com
** Market News International Tokyo Newsroom: 81-3-5403-4835 **

[TOPICS: M$J$$$,M$A$$$,MAJDS$]

Source: http://feedproxy.google.com/~r/forexlive-rss/~3/nAU2qtRM0CY/

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Over 65 million years North American mammal evolution has tracked with climate change

Over 65 million years North American mammal evolution has tracked with climate change

Tuesday, December 27, 2011

History often seems to happen in waves ? fashion and musical tastes turn over every decade and empires give way to new ones over centuries. A similar pattern characterizes the last 65 million years of natural history in North America, where a novel quantitative analysis has identified six distinct, consecutive waves of mammal species diversity, or "evolutionary faunas." What force of history determined the destiny of these groupings? The numbers say it was typically climate change.

"Although we've always known in a general way that mammals respond to climatic change over time, there has been controversy as to whether this can be demonstrated in a quantitative fashion," said Brown University evolutionary biology Professor Christine Janis. "We show that the rise and fall of these faunas is indeed correlated with climatic change ? the rise or fall of global paleotemperatures ? and also influenced by other more local perturbations such as immigration events."

Specifically, of the six waves of species diversity that Janis and her Spanish collaborators describe online this week in the Proceedings of the National Academy of Sciences, four show statistically significant correlations with major changes in temperature. The two transitions that show a weaker but still apparent correlation with the pattern correspond to periods when mammals from other continents happened to invade in large numbers, said Janis, who is the paper's senior and second author.

Previous studies of the potential connection between climate change and mammal species evolution have counted total species diversity in the fossil record over similar time periods. But in this analysis, led by postdoctoral scholar Borja Figueirido, the scientists asked whether there were any patterns within the species diversity that might be significant. They were guided by a similar methodology pioneered in a study of "evolutionary faunas" in marine invertebrates by Janis' late husband Jack Sepkoski, who was a paleontologist at the University of Chicago.

What the authors found is six distinct and consecutive groupings of mammal species that shared a common rise, peak and decline in their numbers. For example, the "Paleocene fauna" had largely given way to the "early-middle Eocene fauna" by about 50 million years ago. Moreover, the authors found that these transfers of dominance correlated with temperature shifts, as reflected in data on past levels of atmospheric oxygen (determined from the isotopes in the fossilized remains of deep sea microorganisms).

By the numbers, the research showed correlations between species diversity and temperature change, but qualitatively, it also provided a narrative of how the traits of typical species within each wave made sense given the changes in vegetation that followed changes in climate. For example, after a warming episode about 20 million years in the early Miocene epoch, the dominant vegetation transitioned from woodland to a savannah-like grassland. It is no surprise, therefore, that many of the herbivores that comprised the accompanying "Miocene fauna" had high-crowned teeth that allowed them to eat the foods from those savannah sources.

To the extent that the study helps clarify scientists' understanding of evolution amid climate changes, it does not do so to the extent that they can make specific predictions about the future, Janis said. But it seems all the clearer that climate change has repeatedly had meaningful effect over millions of years.

"Such perturbations, related to anthropogenic climatic change, are currently challenging the fauna of the world today, emphasizing the importance of the fossil record for our understanding of how past events affected the history of faunal diversification and extinction, and hence how future climactic changes may continue to influence life on earth," the authors wrote in the paper.

###

Brown University: http://www.brown.edu/Administration/News_Bureau

Thanks to Brown University for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 70 time(s).

Source: http://www.labspaces.net/116324/Over____million_years_North_American_mammal_evolution_has_tracked_with_climate_change

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North Korea Projects Image of Stability as Questions Remain About Roles of New Leader, Military

Assessing the stability of North Korea in the wake of Kim Jong Il's death has been a matter of reading between the lines, but there are signs that the communist country's government is at least trying to project the appearance of a smooth transition.

Kim's son, the baby-faced twenty-something Kim Jong Un, is the presumed successor, raising questions about whether the country's military leadership will rally behind him, as it did behind his dictator father. In recent days, state media has disseminated images showing the younger Kim in the company of generals who supported Kim Jong Il.

The footage of the generals and Kim Jong Un, hailed as the military's "supreme commander," was shot on Saturday and shown on state TV on Sunday, as they paid their respects to the late leader.

A source in South Korea told Reuters that it also marked the first time that one of the country's more powerful behind-the-scenes player, Jang Song Thaek, was seen on state TV in a military uniform. Jang was Kim Jong Un's brother-in-law and his chief political lieutenant in recent years.

Another Reuters source suggested that the country was moving from strongman rule to government controlled by multiple leaders.

"Most of the top generals and key party leaders, their family ties with the Kims go back to World War II," Bruce Bechtol, director of the Center for Security Studies at Angelo State University in San Angelo, Texas, told the Wall Street Journal.

The Journal also notes that the dictator in North Korea's government stands in the middle of three competing forces, the political party, the military and the state security department.

"I don't think anyone in the elite would try to grab power (from the dictator) because there is a well-established check-and-balance system. It would be suicidal," Chang Yong-seok, senior researcher at the Institute for Peace and Unification Studies at Seoul National University, told the Journal.

The ongoing shift of power poses new challenges for the Obama administration, which has reacted cautiously to Kim Jong Il's death.

For the past 60 years, the "hermit kingdom" has vexed the United States and its allies with war, nuclear tests, missile launches, belligerence and bellicose bombast. But since he took office, President Obama has had to deal with the country at perhaps its most secretive point: an unclear succession at the very top at a time of deep concern about the stability of the regime.

The kid gloves treatment accorded to the North's youthful new leader has attracted criticism from some who see this is a moment to make a forceful case for dramatic reform and regime change.

But without solid intelligence of the opaque transition process and fearful of misunderstandings that could lead to provocations with the notoriously erratic North, U.S. officials concluded that the best course is to say little, wait and watch.

"All I can say is that we're monitoring the situation closely," White House press secretary Jay Carney said on Wednesday as North Korean state media broadcast pictures of wailing mourners, apparently overcome with grief. "Kim Jong Il had designated Kim Jong Un as his official successor, and at this time we have no indication that that has changed."

Carney added: "We hope that the new North Korean leadership will take the steps necessary to support peace, prosperity and a better future for the North Korean people, including through acting on its commitments to denuclearization."

The Associated Press contributed to this report.

Source: http://feeds.foxnews.com/~r/foxnews/world/~3/sAEUR3lcru0/

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Guide: Coal country has tourism potential in W.Va.

Some of the bloodiest and most important moments in the American labor movement happened in the coalfields of southern West Virginia. But most who live beyond its rugged mountains, and even many who live in them, don't know the stories.

Doug Estepp is trying to change that, one busload of tourists at a time.

Estepp grew up in a coal mining family in Mingo County but never heard much about the early 20th century "mine wars" as a child.

The term covers many events in the long, violent struggle to unionize: a deadly gunfight on the streets of Matewan; the largest armed insurrection since the Civil War in the woods above Blair; the firing of machine guns from an armor-plated train on striking miners and their families in the Holly Grove tent colony.

Estepp set out this past summer to tell the tales. With no experience in the tour-bus industry, he took 80 people on two inaugural trips to prove that a region perhaps best known for mine disasters could become West Virginia's next big destination.

Estepp, a full-time employee of the U.S. Treasury in Martinsburg, made enough money to break even, and he's expanding in 2012 with six trips, including departures from Beckley, Columbus, Pittsburgh, Baltimore, Hampton Roads, Va., and Washington, D.C.

His tour stops show everything from the squalor of company-run camps to coal barons' mansions in Bramwell.

He's also taking his customers' advice and expanding the trips to four days, allowing more time to visit with active and retired miners and the people who re-enact the Matewan Massacre.

"I literally have to drag folks back onto the bus from that one," Estepp says.

Donna May Paterino, who has led the 30-member Matewan re-enactment troupe for 11 seasons, says Estepp's tours helped her put on 12 street theater shows this year, more than ever before. If he keeps coming, she may someday be able to raise the money she needs for an outdoor amphitheater.

The battle of Matewan occurred May 19, 1920, between the skilled marksmen of the Baldwin-Felts Detective Agency and striking miners, some armed with guns from the previous century. Twelve men died.

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"The miners had no rights," Paterino says. "Their backs were strong, but the coal operators thought their minds were weak."

They'd been abused and exploited, paid in company scrip, forced to live in company housing and shop in company stores. Their lives were controlled, their work conditions dangerous, their labor never-ending.

And so they fought for what was then unthinkable. They wanted to be paid by the hour, not the ton. They wanted a week that lasted five days, not seven. They wanted black miners and white miners to be paid equally.

The shootout, depicted in the 1987 John Sayles film "Matewan," was a precursor to the 1921 battle of Blair Mountain, when armed miners clashed with law enforcement officers and hired guns who had fortified pickets, protective trenches, homemade bombs and machine guns.

At least 16 men died in that battle before the miners surrendered to federal troops.

"The struggles were so unreal," Paterino says. "And when you start researching it, you realize it was just the beginning."

Estepp says his clients always have the same question: "Why haven't we heard this before?"

The mine wars, he says, weren't taught in West Virginia schools or included in textbooks.

For generations after the battles, "a lot of folks on both sides just simply wouldn't talk about it," he says. "They didn't want to bring up hard feelings."

Things only began to change after the release of the movie, which was actually shot in the Fayette County town of Thurmond.

Eleanore Hofstetter of Baltimore took one of Estepp's first tours with a friend. "We very much enjoyed it," she said. "It was tremendously educational; we didn't know anything about the coal country wars." She even loved the accommodations in state park lodges: "They're almost like luxury resorts."

Estepp, who studied the conflicts as a student at West Virginia University and graduated with a degree in history, is "electrifying" in his enthusiasm, says Marie Blackwell, head of the Mercer County Convention & Visitors Bureau in Princeton. "His possibilities are endless."

Two years ago, the visitors' bureau was in a branding crisis.

The area doesn't have the same outdoor offerings as counties that capitalize on whitewater rafting, scenic gorges and rock climbing. So Blackwell tested a new theme, "Discover America's Coal Story," at a convention in Columbus. People snatched up brochures and offered to buy the coal figurines she'd brought along.

Blackwell called her staff.

"We're coal and railroads," she told them. "That's what people are after, and that needs to be our branding."

"It's not whether you should or should not mine coal," she says. "We're sharing the stories of how the people have lived and worked, what their lives have been like."

One of Estepp's first stops is the Whipple Company Store in Scarbro, built in 1890 by Justus Collins, who came up with the idea of using Baldwin-Felts men to break strikes and ran his camp like a prison.

Now privately owned, the store has been preserved and turned into a museum. It features a hand-operated freight elevator, post office, switchboard station, two walk-in safes and a secret second floor.

It sets the tone, Estepp says, helping people understand the gap between the men who ran the companies and the laborers who kept them in business.

"We really try to explain each site and how it relates to the next one and the previous one," he says.

Estepp has already branched out to include three Hatfield & McCoy Tours next year, exploring the feud between the legendary families from Kentucky and West Virginia.

If his second year proves successful, Estepp may add even more stops to the Mine War Tour, including the courthouse in Welch where Matewan Police Chief Sid Hatfield was assassinated the year after the gunfight.

He's already got a few reservations.

___

If You Go...

COAL COUNTRY TOURS: http://coalcountrytours.com or 540-233-0543. Four-day trips are $599 per person, double occupancy, all-inclusive (motorcoach, lodging, meals etc.) Departures for 2012 are May 17-20 from Columbus, Ohio; May 24-27 from Washington D.C.; June 7-10 from Pittsburgh; Sept. 13-16 from Hampton Roads, Va.; and Oct. 4-7 from Baltimore. Participants can also meet any of the tours in Beckley, W.Va.

MERCER COUNTY CONVENTION & VISITORS BUREAU: http://www.visitmercercounty.com/ or 800-221-3206.

Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://www.msnbc.msn.com/id/45805971/ns/travel-destination_travel/

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Wednesday, December 28, 2011

Neuralstem's NSI-189 trial in major depressive disorder receives FDA approval to advance to Phase Ib

Neuralstem's NSI-189 trial in major depressive disorder receives FDA approval to advance to Phase Ib [ Back to EurekAlert! ] Public release date: 27-Dec-2011
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Contact: Deanne Eagle
deanneeagle@gmail.com
917-837-5866
Neuralstem, Inc.

First neuroregenerative drug tested in depression

ROCKVILLE, Maryland, December, 27, 2011 Neuralstem, Inc. (NYSE Amex: CUR) announced that it has been approved by the Food and Drug Administration to advance to Phase Ib in its ongoing clinical trial to test its novel neuroregenerative compound, NSI-189, for the treatment of major depressive disorder (MDD). Phase Ib will test the safety and tolerability of the drug in depressed patients. NSI-189 is a proprietary new chemical entity discovered by Neuralstem that stimulates new neuron growth in the hippocampus, an area of the brain that is believed to be involved in MDD as well as other diseases and conditions, such as Alzheimer's disease and post-traumatic stress disorder (PTSD).

"We are pleased to be approved to begin testing NSI-189 in patients who suffer from depression," said Karl Johe, PhD, Chief Scientific Officer and Chairman of Neuralstem's Board of Directors. "Loss of hippocampal volume is a known characteristic in depressed patients. NSI-189 stimulates neurogenesis and increases hippocampal volume in healthy adult mice, at the same time reversing behavioral symptoms in mouse depression models, so it could address depression at the source."

"It is exciting to see a new class of drugs that potentially offers a novel and different approach to this disease moving into patients," said Maurizio Fava, MD, Slater Family Professor of Psychiatry at Harvard Medical School and Executive Vice Chair of the Department of Psychiatry at Massachusetts General Hospital. Dr. Fava, one of the world's leading researchers in MDD, helped design the Neuralstem trial.

About NSI-189

Neuralstem's technology enabled the creation of neural stem cell lines from many areas of the human CNS, including the hippocampus. The hippocampus is a part of the brain involved in memory and the generation of new neurons. It is also implicated in several major neurological and psychiatric diseases. From its hippocampal neural stem cell lines, Neuralstem has created virtually unlimited amounts of mature human neurons and glia in laboratory dishes. These can be used to mimic the natural brain environment in order to test drug effects.

Neuralstem has been engaged in its own drug discovery program with these human hippocampal stem cell lines since 2000. In 2009, Neuralstem was granted U.S. patents on four first-in-class chemical entities that boost the generation of new neurons. NSI-189, the first of these to be in a clinical trial, significantly stimulates the generation of new hippocampal neurons (neurogenesis) in vitro and in animal models, above and beyond the neural stem cells' innate differentiation.

NSI-189 is the lead compound in Neuralstem's neuroregenerative small molecule drug platform, which the company plans to develop into orally administered drugs for MDD and other psychiatric disorders, such as Alzheimer's disease, anxiety, bipolar disorder and post traumatic stress disorder.

NSI-189 stimulated neurogenesis of human hippocampus-derived neural stem cells in-vitro. In healthy normal adult mice, NSI-189 stimulated neurogenesis in the hippocampus and significantly increased its volume, apparently by increasing its synaptic network after 28 days of daily oral administration. In mouse models of depression, NSI-189 significantly improved behavioral responses associated with depression. In humans, NSI-189 may reverse the human hippocampal atrophy seen in MDD and other disorders and reverse their symptoms. This program has received significant support from both the Defense Advanced Research Projects Agency (DARPA) and the National Institutes of Health (NIH).

About the Trial

The NSI-189/MDD trial is a randomized, double-blind, placebo-controlled, multiple-dose escalating trial evaluating the safety, tolerability, pharmacokinetics and pharmacodynamic effect of NSI-189 in the treatment of MDD. Phase Ia tested escalating doses of single administration of NSI-189 in healthy patients. Phase Ib will test the safety of escalating doses of NSI-189 for 28 daily administrations in 24 depressed patients. The Phase Ib portion of the trial is expected to take approximately six months to complete.

###

About Neuralstem

Neuralstem's patented technology enables the ability to produce neural stem cells of the human brain and spinal cord in commercial quantities, and the ability to control the differentiation of these cells constitutively into mature, physiologically relevant human neurons and glia. Neuralstem is in an FDA-approved Phase I safety clinical trial for amyotrophic lateral sclerosis (ALS), often referred to as Lou Gehrig's disease and has been awarded orphan status designation by the FDA.

In addition to ALS, the company is also targeting major central nervous system conditions with its cell therapy platform, including spinal cord injury, ischemic spastic paraplegia, chronic stroke, and Huntington's disease. The company has submitted an IND (Investigational New Drug) application to the FDA for a Phase I safety trial in chronic spinal cord injury.

Neuralstem also has the ability to generate stable human neural stem cell lines suitable for the systematic screening of large chemical libraries. Through this proprietary screening technology, Neuralstem has discovered and patented compounds that may stimulate the brain's capacity to generate new neurons, possibly reversing the pathologies of some central nervous system conditions. The company has received approval from the FDA to conduct a Phase Ib safety trial evaluating NSI-189, its first small molecule compound, for the treatment of major depressive disorder (MDD). Additional indications could include schizophrenia, Alzheimer's disease and bipolar disorder.

For more information, please go to www.neuralstem.com.

Cautionary Statement Regarding Forward Looking Information

This news release may contain forward-looking statements made pursuant to the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Investors are cautioned that such forward-looking statements in this press release regarding potential applications of Neuralstem's technologies constitute forward-looking statements that involve risks and uncertainties, including, without limitation, risks inherent in the development and commercialization of potential products, uncertainty of clinical trial results or regulatory approvals or clearances, need for future capital, dependence upon collaborators and maintenance of our intellectual property rights. Actual results may differ materially from the results anticipated in these forward-looking statements. Additional information on potential factors that could affect our results and other risks and uncertainties are detailed from time to time in Neuralstem's periodic reports, including the annual report on Form 10-K for the year ended December 31, 2010 and the quarterly report on Form 10-Q for the period ended September 30, 2011.


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Neuralstem's NSI-189 trial in major depressive disorder receives FDA approval to advance to Phase Ib [ Back to EurekAlert! ] Public release date: 27-Dec-2011
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Contact: Deanne Eagle
deanneeagle@gmail.com
917-837-5866
Neuralstem, Inc.

First neuroregenerative drug tested in depression

ROCKVILLE, Maryland, December, 27, 2011 Neuralstem, Inc. (NYSE Amex: CUR) announced that it has been approved by the Food and Drug Administration to advance to Phase Ib in its ongoing clinical trial to test its novel neuroregenerative compound, NSI-189, for the treatment of major depressive disorder (MDD). Phase Ib will test the safety and tolerability of the drug in depressed patients. NSI-189 is a proprietary new chemical entity discovered by Neuralstem that stimulates new neuron growth in the hippocampus, an area of the brain that is believed to be involved in MDD as well as other diseases and conditions, such as Alzheimer's disease and post-traumatic stress disorder (PTSD).

"We are pleased to be approved to begin testing NSI-189 in patients who suffer from depression," said Karl Johe, PhD, Chief Scientific Officer and Chairman of Neuralstem's Board of Directors. "Loss of hippocampal volume is a known characteristic in depressed patients. NSI-189 stimulates neurogenesis and increases hippocampal volume in healthy adult mice, at the same time reversing behavioral symptoms in mouse depression models, so it could address depression at the source."

"It is exciting to see a new class of drugs that potentially offers a novel and different approach to this disease moving into patients," said Maurizio Fava, MD, Slater Family Professor of Psychiatry at Harvard Medical School and Executive Vice Chair of the Department of Psychiatry at Massachusetts General Hospital. Dr. Fava, one of the world's leading researchers in MDD, helped design the Neuralstem trial.

About NSI-189

Neuralstem's technology enabled the creation of neural stem cell lines from many areas of the human CNS, including the hippocampus. The hippocampus is a part of the brain involved in memory and the generation of new neurons. It is also implicated in several major neurological and psychiatric diseases. From its hippocampal neural stem cell lines, Neuralstem has created virtually unlimited amounts of mature human neurons and glia in laboratory dishes. These can be used to mimic the natural brain environment in order to test drug effects.

Neuralstem has been engaged in its own drug discovery program with these human hippocampal stem cell lines since 2000. In 2009, Neuralstem was granted U.S. patents on four first-in-class chemical entities that boost the generation of new neurons. NSI-189, the first of these to be in a clinical trial, significantly stimulates the generation of new hippocampal neurons (neurogenesis) in vitro and in animal models, above and beyond the neural stem cells' innate differentiation.

NSI-189 is the lead compound in Neuralstem's neuroregenerative small molecule drug platform, which the company plans to develop into orally administered drugs for MDD and other psychiatric disorders, such as Alzheimer's disease, anxiety, bipolar disorder and post traumatic stress disorder.

NSI-189 stimulated neurogenesis of human hippocampus-derived neural stem cells in-vitro. In healthy normal adult mice, NSI-189 stimulated neurogenesis in the hippocampus and significantly increased its volume, apparently by increasing its synaptic network after 28 days of daily oral administration. In mouse models of depression, NSI-189 significantly improved behavioral responses associated with depression. In humans, NSI-189 may reverse the human hippocampal atrophy seen in MDD and other disorders and reverse their symptoms. This program has received significant support from both the Defense Advanced Research Projects Agency (DARPA) and the National Institutes of Health (NIH).

About the Trial

The NSI-189/MDD trial is a randomized, double-blind, placebo-controlled, multiple-dose escalating trial evaluating the safety, tolerability, pharmacokinetics and pharmacodynamic effect of NSI-189 in the treatment of MDD. Phase Ia tested escalating doses of single administration of NSI-189 in healthy patients. Phase Ib will test the safety of escalating doses of NSI-189 for 28 daily administrations in 24 depressed patients. The Phase Ib portion of the trial is expected to take approximately six months to complete.

###

About Neuralstem

Neuralstem's patented technology enables the ability to produce neural stem cells of the human brain and spinal cord in commercial quantities, and the ability to control the differentiation of these cells constitutively into mature, physiologically relevant human neurons and glia. Neuralstem is in an FDA-approved Phase I safety clinical trial for amyotrophic lateral sclerosis (ALS), often referred to as Lou Gehrig's disease and has been awarded orphan status designation by the FDA.

In addition to ALS, the company is also targeting major central nervous system conditions with its cell therapy platform, including spinal cord injury, ischemic spastic paraplegia, chronic stroke, and Huntington's disease. The company has submitted an IND (Investigational New Drug) application to the FDA for a Phase I safety trial in chronic spinal cord injury.

Neuralstem also has the ability to generate stable human neural stem cell lines suitable for the systematic screening of large chemical libraries. Through this proprietary screening technology, Neuralstem has discovered and patented compounds that may stimulate the brain's capacity to generate new neurons, possibly reversing the pathologies of some central nervous system conditions. The company has received approval from the FDA to conduct a Phase Ib safety trial evaluating NSI-189, its first small molecule compound, for the treatment of major depressive disorder (MDD). Additional indications could include schizophrenia, Alzheimer's disease and bipolar disorder.

For more information, please go to www.neuralstem.com.

Cautionary Statement Regarding Forward Looking Information

This news release may contain forward-looking statements made pursuant to the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Investors are cautioned that such forward-looking statements in this press release regarding potential applications of Neuralstem's technologies constitute forward-looking statements that involve risks and uncertainties, including, without limitation, risks inherent in the development and commercialization of potential products, uncertainty of clinical trial results or regulatory approvals or clearances, need for future capital, dependence upon collaborators and maintenance of our intellectual property rights. Actual results may differ materially from the results anticipated in these forward-looking statements. Additional information on potential factors that could affect our results and other risks and uncertainties are detailed from time to time in Neuralstem's periodic reports, including the annual report on Form 10-K for the year ended December 31, 2010 and the quarterly report on Form 10-Q for the period ended September 30, 2011.


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2011-12/ni-nnt122711.php

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Pantech Pocket review


Hundreds of smartphones of all shapes, sizes and colors pass through the doors of Engadget HQ every year, so it's natural for a few oddball devices with crazy form factors to end up in our hands from time to time. The Motorola Flipout, LG DoublePlay, Kyocera Echo and Samsung DoubleTime are all instances of carriers trying something new, seeing what sticks. Of course, pushing out a phone with an unproven form factor is a huge gamble for a mobile provider, and as a result they only ship to stores in low volume and rarely receive any kind of marketing campaign at its launch. Indeed, the vast majority of these types of phones are low-end devices aimed at young adults and first-time smartphone buyers, but we still find it adventurous to take a break from the monotony of black slabs and try out something completely different.

The Pantech Pocket is definitely unique -- not because it flips or slides a weird way or because it has two and a half screens, but because its 4-inch display, whose 4:3 aspect ratio promises 20 percent more horizontal real estate. Did AT&T's gamble on the display pay off? Is it worth the $50 that AT&T demands with a two-year commitment attached? Time to find out below.

Continue reading Pantech Pocket review

Pantech Pocket review originally appeared on Engadget on Tue, 27 Dec 2011 16:35:00 EDT. Please see our terms for use of feeds.

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Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/IJs5k2LyIl8/

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[OOC] Trained 2 Kill

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Oil hovers below $100 amid low holiday volume

SINGAPORE (AP) - Oil prices hovered below $100 a barrel Tuesday in Asia amid low holiday week trading volume.

Benchmark crude for February delivery was down 11 cents at $99.57 a barrel at early afternoon Singapore time in electronic trading on the New York Mercantile Exchange. The contract rose 15 cents to settle at $99.68 in New York on Friday.

In London, Brent crude was up 15 cents at $108.11 a barrel on the ICE Futures exchange.

Global oil trading markets were closed Monday for the Christmas holiday.

Crude briefly popped above $100 on Friday amid growing evidence the U.S. economy is improving. Some analysts say concerns that Europe's debt crisis will trigger a recession on the continent next year will overshadow any positive news out of the U.S. this week.

"We don't expect this strength to be maintained this week given a likely shift in focus back toward the eurozone where major debt issues remain largely unresolved," energy consultant Ritterbusch and Associates said in a report.

Because many traders are on vacation this week, trading volume is sharply lower and a few trades could jolt prices.

"Volume will be thin through this abbreviated week," energy consultant and trader The Schork Group said in a report. "As such, the potential exists for some wild swings."

In other Nymex trading, heating oil rose 0.8 cents to $2.91 per gallon and gasoline futures were steady at $2.68 per gallon. Natural gas futures were down 2.9 cents to $3.09 per 1,000 cubic feet.


Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://www.breitbart.com/article.php?id=D9RSMFEO0&show_article=1

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Tuesday, December 27, 2011

'Magic Mike' First Look: Channing Tatum Hits The Stage

If you ever wondered what a Steven Soderbergh stripper movie might look like (and come on, I know I'm not the only one out there who's wondered about that) well, wonder no more.
The Academy Award-winning director's upcoming film about hot dudes who take their clothes off for money ? "Magic Mike," perhaps better known [...]

Source: http://moviesblog.mtv.com/2011/12/27/magic-mike-channing-tatum-first-look/

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Some NFL players still willing to hide concussions (AP)

Ask Jacksonville Jaguars running back Maurice Jones-Drew whether he would try to play through a concussion or yank himself from a game, and he'll provide a straightforward answer.

"Hide it," the NFL's leading rusher said.

"The bottom line is: You have to be able to put food on the table. No one's going to sign or want a guy who can't stay healthy. I know there will be a day when I'm going to have trouble walking. I realize that," Jones-Drew said. "But this is what I signed up for. Injuries are part of the game. If you don't want to get hit, then you shouldn't be playing."

Other players say they would do the same: Hide it.

In a series of interviews about head injuries with The Associated Press over the last two weeks, 23 of 44 NFL players ? slightly more than half ? said they would try to conceal a possible concussion rather than pull themselves out of a game. Some acknowledged they already have. Players also said they should be better protected from their own instincts: More than two-thirds of the group the AP talked to wants independent neurologists on sidelines during games.

The AP spoke to a cross-section of players ? at least one from each of the 32 NFL teams ? to gauge whether concussion safety and attitudes about head injuries have changed in the past two years of close attention devoted to the issue. The group included 33 starters and 11 reserves; 25 players on offense and 19 on defense; all have played at least three seasons in the NFL.

The players tended to indicate they are more aware of the possible long-term effects of jarring hits to their heads than they once were. In a sign of the sort of progress the league wants, five players said that while they would have tried to conceal a concussion during a game in 2009, now they would seek help.

"You look at some of the cases where you see some of the retired players and the issues that they're having now, even with some of the guys who've passed and had their brains examined ? you see what their brains look like now," said Washington Redskins linebacker London Fletcher, the NFL's leading tackler. "That does play a part in how I think now about it."

But his teammate, backup fullback Mike Sellers, said he's hidden concussions in the past and would "highly doubt" that any player would willingly take himself out of a game.

"You want to continue to play. You're a competitor. You're not going to tell on yourself. There have been times I've been dinged, and they've taken my helmet from me, and ... I'd snatch my helmet back and get back on the field," Sellers said. "A lot of guys wouldn't say anything because a lot of guys wouldn't think anything during the game, until afterward, when they have a headache or they can't remember certain things."

San Francisco 49ers defensive lineman Justin Smith captured a popular sentiment: Players know of the potential problems, yet would risk further damage.

"It doesn't take a rocket scientist to figure out if (you have) a concussion, you're probably damaging your brain a little bit. Just like if you sprain your wrist a bunch, you're going to have some wrist problems down the road. Yeah, I'd still play through it. It's part of it. It's part of the game," Smith said. "I think if you're noticeably messed up, yeah, they'll take you out. But if you've just got some blurry vision, I'd say that's the player's call. And most guys ? 99 percent of guys in the NFL ? are going to play through it."

Smith said he sustained one concussion in high school ("You don't know who you are," is how he described it) and another in college ("Walking around the whole time, but I don't remember anything until six hours later").

The NFL likes to say that views about concussions have shifted from simply accepting they're part of the sport to doing what's possible to lessen impacts. Commissioner Roger Goodell talks about "changing the culture," so players don't try to "walk it off" after taking hits to the head.

Yet the AP's conversations with players showed there is room for more adjustments, which did not surprise Dr. Richard Ellenbogen, co-chairman of the NFL's head, neck and spine committee.

"The culture change takes awhile," Ellenbogen said in a telephone interview. "Why would these guys want to go out? They love playing the game. They don't want to leave their team. They want to win. I understand all that. And that's why we have to be on our toes with coming up with exams that are hard to beat, so to speak."

New Orleans Saints offensive lineman Zach Strief put it this way: "We all grew up with, `Hey, get back in there. You (only) got your bell rung.' And while it's changing now, I think it's going to take time for the mindset to change."

A few players said they'd be particularly inclined to hide a concussion if it happened in a playoff game or the Super Bowl. Some said their decision would depend on the severity of a head injury ? but they'd hide it if they could.

Clearly, there is a stigma associated with leaving the field, no matter the reason. Indeed, one player who said he'd exit a game if he thought he might have a concussion didn't want to be quoted on the subject.

Other findings from the interviews:

_Asked whether the NFL should have independent neurologists at games to examine players and determine if they should be held out because of concussions, 31 players said "yes," and 10 said "no." Three didn't answer.

"They've got guys looking at your uniform to make sure you're wearing the right kind of socks," St. Louis Rams safety Quintin Mikell said. "Why not have somebody there to protect your head? I think we definitely should have that."

He said he's tried to clear his head and stay on the field "many times."

"I'll probably pay for it later in my life," Mikell said, "but at the same time, I'll probably pay for the alcohol that I drank or driving fast cars. It's one of those things that it just comes with the territory."

_Specifically regarding concussions, 28 of the 44 players think playing in the NFL is safer now than in 2009, while 13 think it's the same, and two think it's more dangerous. One wasn't sure. Those who think safety has improved gave credit to the rise in awareness; more fines for illegal hits; this season's changes to kickoff rules that have cut down on the number of returns; and the new labor contract's reduction in the amount of contact allowed in practice.

"When I first came into the league, it was like, `Whatever goes.' It was more of that old-school, just `beat-him-up' football. Not wanting to hurt anybody, but show how tough you were. Back in the day, it was like if you come out (of a game) with (a) slight concussion, then you weren't giving it all for your team," Buffalo Bills linebacker Andra Davis said. "But now, they're taking that option away from you."

Davis, a 10th-year veteran who turned 33 on Friday and said he's had a couple of concussions, is one of those whose view on seeking help for such injuries has changed.

"The younger me would definitely hide it," Davis said. "But the older me now ? with wife and kids and looking more at life after football ? I would say something about it."

_Asked whether more can be done to protect players from head injuries, 18 players said "yes," and 24 said "no." Two did not respond.

Not surprisingly, there were divisions according to position, and players on opposite sides of the ball generally drifted toward opposing views: Those on offense seemed more likely than those on defense to say more can ? and should ? be done to improve safety. Linemen, meanwhile, often complained that there is no way to improve their plight, with the helmet-to-helmet banging that takes place at the snap on play after play. One player described those collisions as "micro-episodes that build up over time."

Nearly three-quarters of the players who told the AP they think safety can improve ? 13 of 18 ? suggested equipment can be improved, too. Helmet technology, mouth guards and chin straps all were mentioned.

Two players suggested more education about concussions is needed.

Dr. Robert Cantu, a senior adviser to Ellenbogen's NFL committee who said he is consulted regularly by the league, insisted that while there has been progress, there is still work to be done.

"Has there been a culture change overall? I think the answer is, unquestionably, `yes.' Could there be more done? Yes. Do all the players get it? No. Do they want to get it? No," said Cantu, a clinical professor of neurosurgery and co-director of the Center for the Study of Traumatic Encephalopathy at Boston University School of Medicine.

CTE is a degenerative disease increasingly found in football players and other athletes who have absorbed repeated blows to the head. It has been linked to memory loss, disorientation, poor decision-making, and depression that can lead to drug use and, as in the case of former Chicago Bears defensive back Dave Duerson, even suicide.

The league distributed informational posters in 2010 to warn about the dangers of head injuries, but Cantu said: "Just because the posters are in every locker room, it's not mandatory reading. Or people can say they read it but not really have read it."

"More stress needs to be placed ? and I believe this is the players association's responsibility as much as it is the NFL's ? on the dangers of playing symptomatic with a concussion and more knowledge needs to be imparted on chronic traumatic encephalopathy, which obviously does exist in the NFL. ... All of those sub-concussive blows count, and you need to minimize the amount of brain trauma that you take," Cantu said.

Union spokesman George Atallah declined a request for comment about concussions.

Little-discussed until reporting by The New York Times led to an October 2009 congressional hearing on concussions in the NFL, head injuries are now part of the daily conversation about professional football. On Saturday alone, two starting quarterbacks, Cleveland's Colt McCoy and Arizona's Kevin Kolb, sat out because of head injuries, while a third, Minnesota's Christian Ponder, left his team's game with what his coach called "concussionlike symptoms."

According to data from STATS LLC, from 2000-09, an average of 3.1 NFL players ? and never more than nine in an entire season ? went on injured reserve because of a concussion or head injury. That number rose to 18 last season, and stood at 17 through Week 15 this season.

Similarly, STATS LLC said, over that same 10-year span at the start of the century, an average of 26 NFL players each season were listed on the weekly injury report and missed games because of a concussion or head injury. That number rose to 89 in 2010, and stood at 75 this season through Saturday's games.

At least eight lawsuits have been filed against the NFL in recent months ? including three within the last week ? by dozens of former players who say they have medical problems related to brain injuries from their time in professional football. The NFL's stance, in part, is that players knew there were risks of injury, and there was no misconduct or liability on the league's part.

"It's a physical sport. Guys are going to get hit in the head. When we're young, when we start playing this sport, we know what we're getting into," Philadelphia Eagles tight end Brent Celek said. "It's not like, `Oh, I'm going to play this because my head's going to be fine when I'm done playing.' It's a risk you take playing this game, but I think the league is doing everything in their power to make it as safe as possible."

The NFL certainly has found itself adjusting on the fly.

One example: After San Diego Chargers offensive lineman Kris Dielman got a concussion but stayed in the lineup in October, then had a seizure on a team flight, the NFL said it would give game officials "concussion awareness training" so they could keep an eye out for players.

A few players interviewed by the AP mentioned the recent case of Cleveland's McCoy, who has missed two consecutive games after a shot to the helmet from Pittsburgh Steelers linebacker James Harrison. McCoy was not checked for a concussion during the game against Pittsburgh and went back in; Harrison was suspended for a game; starting with this week's games, the league put certified athletic trainers in booths above the field to watch for injuries. The trainers aren't there to diagnose or prescribe treatment, the NFL said, but are supposed to call down to team medical staffs to alert them there could be a problem.

Some think the league could go further.

"I don't think it's sufficient. I think it's a great first step," BU's Cantu said, mentioning a study that showed concussions were noticed more in junior hockey when there was an observer at the rink.

While Cantu, like players interviewed by the AP, is in favor of having independent neurosurgeons at games rather than only team-employed doctors ? something raised as a possibility in 2009 but never done ? NFL committee co-chairman Ellenbogen said the more pressing issue was "the ability to see all the players on the field."

"Team doctors are pretty concerned about concussions, and I don't think they're people that are going to be bought and sold. ... If the real problem is the doctors are being influenced by the coaches, then we've got to fix that," said Ellenbogen, chairman of the department of neurological surgery at the University of Washington School of Medicine. "If the (players' union) says, `We want independent neurologists,' we'll discuss that. ... To be honest with you, we ain't done. When our committee meets with the team physicians after the Super Bowl, everything's on the table. You think this is the last rendition of what we do? Heck, no. We're not done."

As it is, while the players the AP spoke to tend to feel better about the way concussions are handled now than in 2009, they won't deny that dangers lurk.

"You're never going to be totally safe from concussions in this game," Oakland Raiders cornerback Stanford Routt said. "This is the only place where you can actually legally assault people."

___

AP Sports Writers Bob Baum, Tim Booth, Tom Canavan, Chris Duncan, Josh Dubow, R.B. Fallstrom, Dave Ginsburg, Fred Goodall, Pat Graham, Will Graves, Stephen Hawkins, George Henry, Chris Jenkins, Joe Kay, Jon Krawczynski, Larry Lage, Mark Long, Rob Maaddi, Michael Marot, Brett Martel, Janie McCauley, Steve Reed, Andrew Seligman, Dave Skretta, Howard Ulman, Teresa M. Walker, Dennis Waszak Jr., John Wawrow, Bernie Wilson, Steven Wine, and Tom Withers contributed to this report.

___

Howard Fendrich is on Twitter at http://twitter.com/HowardFendrich

Source: http://us.rd.yahoo.com/dailynews/rss/topstories/*http%3A//news.yahoo.com/s/ap/20111225/ap_on_sp_fo_ne/fbn_nfl_concussions_two_years_later

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